MrCarlos Matellan

Our work is focused on understanding how different elements of the tumour microenvironment, such as the extracellular matrix and cancer associated fibroblasts modulate the behaviour of immune cells in cancer, contributing to immune dysfunction and immunosuppression. 

To this end we implement a range of immunology, molecular biology and mechanobiology techniques, as well as 3D cultures and microfluidic platforms to recapitulate and interrogate stroma-immune interactions.