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Dr Debra Higgins

Dr

Debra Higgins

Biomedical Research Advisor
Central Office - College of Health and Agricultural Sciences
01 716 7751
University College Dublin, Central Office - College of Health and Agricultural Sciences, Conway Institute Belfield Dublin 4

PUBLICATIONS

Showing 1-25 out of 48
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JOURNAL ARTICLE
1 Dec 2017Biochimica et Biophysica Acta - Molecular Basis of Disease1863(12):3095-3104
Higgins DF, Ewart LM, Masterson E, Tennant S, Grebnev G...
JOURNAL ARTICLE
Profibrotic IHG-1 complexes with renal disease associated HSPA5 and TRAP1 in mitochondria
1 Apr 2017Biochimica et Biophysica Acta - Molecular Basis of Disease1863(4):896-906
Bhreathnach U, Griffin B, Brennan E, Ewart L, Higgins D...
JOURNAL ARTICLE
Wnt6 regulates epithelial cell differentiation and is dysregulated in renal fibrosis
1 Jul 2016American Journal of Physiology - Renal Physiology311(1):F35-F45
Beaton H, Andrews D, Parsons M, Murphy M, Gaffney A...
JOURNAL ARTICLE
Hypoxia promotes production of neural crest cells in the embryonic head
15 May 2016Development (Cambridge)143(10):1742-1752
Scully D, Keane E, Batt E, Karunakaran P, Higgins DF...
JOURNAL ARTICLE
BMP-7 inhibits renal Akt signalling.
1 Jan 2015Journal of the American Society of Nephrology : JASN26((NA)):425A
CONFERENCE CONTRIBUTION
N/A
1 Jan 2015The role of miR302 and Let7 in macrophage polarisation.Journal of the American Society of Nephrology : JASN26((NA)):695A
JOURNAL ARTICLE
Epigenetic unsilencing reverses renal fibrosis
1 May 2014Journal of the American Society of Nephrology25(5):865-866
Higgins DF, Murphy M
JOURNAL ARTICLE
The role of hypoxia-inducible transcription factors in determination of macrophage phenotypes.
1 Jan 2014Journal of the American Society of Nephrology : JASN25((NA)):1069A
CONFERENCE PAPER
DIABETIC KIDNEY DISEASE AFTER METABOLIC SURGERY
1 Dec 2013IRISH JOURNAL OF MEDICAL SCIENCE182:S490-S491 (2 pages)
Lucey H, Elliot J, Higgins DF, Neff KJ, le Roux CW
JOURNAL ARTICLE
IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-beta1-induced fibrotic responses
1 Aug 2013Biochimica et biophysica acta1833(8):1969-1978
JOURNAL ARTICLE
IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses
1 Aug 2013Biochimica et Biophysica Acta - Molecular Cell Research1833(8):1969-1978
Corcoran JB, McCarthy S, Griffin B, Gaffney A, Bhreathnach U...
JOURNAL ARTICLE
Lipoxins Attenuate Renal Fibrosis by Inducing let-7c and Suppressing TGF beta R1
1 Apr 2013JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY24(4):627-637 (11 pages)
Brennan EP, Nolan KA, Boergeson E, Gough OS, McEvoy CM...
JOURNAL ARTICLE
Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1
29 Mar 2013Journal of the American Society of Nephrology24(4):627-637
Brennan EP, Nolan KA, Börgeson E, Gough OS, McEvoy CM...
JOURNAL ARTICLE
Lipoxin A4 and Resolvin E1 reduce inflammatory monocytes in hemodialysis patients.
1 Jan 2013Journal of the American Society of Nephrology : JASN24((NA)):716A
CONFERENCE PAPER
Wnt6 regulates epithelial cell fate specification during kidney development and in adult renal cells.
1 Jan 2013MOLECULAR BIOLOGY OF THE CELL24:2 pages
Beaton H, Kavanagh D, Gaffney A, Andrews D, Murphy M...
JOURNAL ARTICLE
DO EMBRYOS AND CANCER CELLS SHARE A COMMON MECHANISM FOR EPITHELIAL-TO-MESENCHYMAL TRANSITION?
1 Dec 2012IRISH JOURNAL OF MEDICAL SCIENCE181:S443 (1 page)
Karunakaran P, Keane E, Higgins D, Itasaki N
CONFERENCE PAPER
Wnt 6 is increased in diabetic nephropathy and modulates de novo tubulogenesis and opposes TGFbeta mediated epithelial cell differentiation in vitro.
1 Nov 2012American Society of Nephrology
JOURNAL ARTICLE
Lipoxin A<inf>4</inf>attenuates adipose inflammation
1 Oct 2012FASEB Journal26(10):4287-4294
Börgeson E, McGillicuddy FC, Harford KA, Corrigan N, Higgins DF...
JOURNAL ARTICLE
Lipoxin A4 and Resolvin E1 reduce the CD16+ pro-inflammatory subsets of monocytes.
1 Jan 2012Journal of the American Society of Nephrology : JASN23((NA)):564A
JOURNAL ARTICLE
Protecting against obesity-induced chronic kidney disease using pro-resolving lipids.
1 Jan 2012Journal of the American Society of Nephrology : JASN23((NA)):918A
JOURNAL ARTICLE
Wnt6 is increased in diabetic nephropathy and modulates de novo tubulogenesis and opposes TGF-beta mediated epithelial cell differentiation in vitro.
1 Jan 2012Journal of the American Society of Nephrology : JASN23((NA)):146A
JOURNAL ARTICLE
Lipoxin A <inf>4</inf> and benzo-lipoxin A <inf>4</inf> attenuate experimental renal fibrosis
1 Sep 2011FASEB Journal25(9):2967-2979
Börgeson E, Docherty NG, Murphy M, Rodgers K, Ryan A...
CONFERENCE CONTRIBUTION
Maladaptive role of chronic HIF stabilisation in renal disease
8 Jan 2011Oxygen 2011
JOURNAL ARTICLE
Lipoxin A4 reprograms CD16+ mononuclear cells.
1 Jan 2011Journal of the American Society of Nephrology : JASN22((NA)):140A
JOURNAL ARTICLE
Lipoxin A4 and Benzo-Lipoxin A4 protect against renal fibrosis.
1 Jan 2010Journal of the American Society of Nephrology : JASN21((NA)):617A
Showing 1-25 out of 48
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