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Dr Graham Hughes


Graham Hughes

Lecturer/Assistant Professor (Ad Astra Fellow)
School of Biology and Environmental Science
University College Dublin, School of Biology and Environmental Science


I am interested in the use of bioinformatics to address problems in molecular biology, evolution and comparative genomics. My primary interests line in in using comparative genomics and phylomedicine to explore and inform sensory disease, and to understand the evolution of sensory systems, gene adaptations and life history traits from a genomics perspective. I am also interested in understanding genome features in ancient animals. I have written and developed algorithms and workflows for genome projects, with a focus on genome annotation in low-quality datasets, maximizing information usage. My research goals are two-fold: (1) understanding the genomic changes linked to novel adaptations in model and non-model organisms; and (2) develop the appropriate methods and tools for genomic-scale analyses. In my research career, I have applied these goals to a range of extant (bacteria, mammals, birds, reptiles, amphibians, fish) and extinct (Neanderthals, Denisovans, Dinosaurs) species.