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Dr Jens Rauch

Dr

Jens Rauch

Research Fellow
School of Medicine
01 716 6337
University College Dublin, School of Medicine, Systems Biology Ireland Temple Street Dublin 1

BIO

After graduating in Biochemistry from the University of Leipzig, Germany, in 2001 I started my PhD in the Clinical Cooperation Group Molecular Oncology at the University of Munich, Germany, where I developed novel proteomic approaches to investigate new tumour markers for head and neck carcinomas. In 2006, I moved to the Beatson Institute for Cancer Research, Glasgow, UK, as a post-doctoral researcher, where I investigated cancer related cellular signalling pathways using proteomics. I joined Systems Biology Ireland as a postdoctoral researcher in SBI in 2009 and currently lead SBI's Melanoma Research Group. My main focus is the analysis of crucial signalling complexes responsible for resistance mechanisms in malignant melanomas.Professional & Research Experience04/14 - nowSystems Biology Ireland, University College DublinResearch Fellow, Junior Group Leader- Malignant melanomas and acquired resistance mechanisms to clinically used targeted therapies. - Understanding the underlying network adaptations of drug resistance in order to design personalized drug combinations that can avoid or overcome this resistance.10/09 - 04/14 Systems Biology Ireland, University College DublinPost-doctoral Fellow with Prof Walter Kolch- Elucidation of novel insights of ARAF function in cancer, including the use of systems biology approaches to develop mathematical models and clinical data.- Characterization of the scaffold proteins KSR1/2 deciphering their dynamic interactomes. 01/07 - 09/09The Beatson Institute for Cancer Research, Glasgow Post-doctoral Fellow, Proteomics & Signaling Networks Group.- Functional validation of the head and neck cancer antigen hnRNPH identified during my PhD thesis resulting in two first-author publications.11/01 - 09/02IMGM Laboratories GmbH, Martinsried, GermanyAssistant Project Manager Pharmacogenetics- Assay development for pharmacogenetics, SNP analysis, and Real-time PCR for allelic discrimination. - I co-developed and designed the DrugProfilerTM Database for connecting Pharmindex with pharmacogenetic discriminants.Academic Qualifications07/02-09/06University of Munich, Germany, Prof. Dr. Olivier GiresPhD in Biochemistry (Dr. rer. nat.): magna cum laude- Development of mass spectrometry-based techniques to detect novel biomarkers for cancer. These experiments provided several successful tumor markers for early-stage head and neck squamous cell carcinomas and led to five publications.10/01University of Leipzig, Germany Master of Science (Diplom) in Biochemistry - Diploma thesis with Prof. Dr. Annette Beck-Sickinger10/96 - 10/01University of Leipzig, Germany