ProfessorBoris Kholodenko

Full Professor of Systems Biology and Director of Computational Modelling

School of Medicine

  • Full Professor of Systems Biology and Director of Computational Modelling
    School of Medicine
  • 01 716 6304
  • University College Dublin, School of Medicine, Systems Biology Ireland Belfield Dublin 4

RESEARCH INTERESTS

The focus of my work is to bridge the gap between the molecular and cell systems levels of analysis to quantitatively understand and control integrative responses of living cells. A major goal of my current research is to elucidate emerging properties of molecular pathogenetic networks in order to identify and mechanistically understood tumourigenic cell network vulnerabilities, which lend themselves as a basis for new approaches to the diagnosis and therapeutic treatment.

GRANTS

  • GRANT
    FEATURED
    Featured
    Connecting genotype and phenotype by reconstruction and dynamic modelling of adaptive signal transduction networks (DYNEMAR)
    Enterprise Ireland (EI)15 Jun 2016 - 14 Mar 2017
    People funded by this grant:
    • Kholodenko B
  • GRANT
    FEATURED
    Featured
    Synthetic Cellular Signaling Circuits (SynSignal)
    Ec Framework (Fp7)1 Nov 2013 - 31 Oct 2017
    People funded by this grant:
    • Kholodenko B
  • GRANT
    FEATURED
    Featured
    Walton Fellowship: Dynamic rewiring of Rho family GTPase signalling fluxes in cancer cell invasion
    Science Foundation Ireland (SFI)1 Mar 2012 - 31 Aug 2012
    People funded by this grant:
    • Kholodenko B
  • GRANT
    FEATURED
    Featured
    Modeling and Experimental Studies of Cellular Signal Transduction Networks
    Riken1 Jun 2009 - 31 Mar 2011
    People funded by this grant:
    • Kholodenko B
  • GRANT
    Guanine Nucleotide Inhibitor binding governs the protrusion-retraction process in migrating cells.
    University College Dublin (UCD)1 May 2013 - 31 Oct 2014
    People funded by this grant:
    • Kholodenko B
  • GRANT
    Japan Society for the Promotion of Science1 Apr 2011 - 31 Mar 2012
    People funded by this grant:
    • OKADA M,
    • MITOSCH K,
    • support S,
    • Yumoto N,
    • Iwamoto K
  • GRANT
    PRTLI 5: SimSci - Split Accounts School of Mathematical Sciences
    Higher Education Authority (HEA)1 Mar 2011 - 29 Feb 2016
    People funded by this grant:
  • GRANT
    CRC50: Modelling synergistic combinations
    Astrazeneca Uk Ltd.13 Nov 2009 - 12 Nov 2011
    People funded by this grant:
  • GRANT
    Stokes Professorship
    Science Foundation Ireland (SFI)31 Jan 2009 - 30 Jan 2014
    People funded by this grant:
    • Kholodenko B,
    • Kolch W